The publishing of the sequence of human genome in 2001 turned out to be a hallmark achievement. Since then, it has been viewed how this sequencing is going to various aspects like the understanding of the healthcare model. The ability to sequence at a faster and affordable rate has given credence to the concept of personalized medicine as well.
The idea is to provide medicine based upon DNA sequence. Owing to sequencing, the function of many genes and what is their impact from disease point of view is understandable. For instance, the role of BRCA genes for causing breast cancer has been studied using genome wide analysis studies. The same case applies for the role of single nucleotide polymorphism (SNP) and how it is important in causing some diseases. Furthermore, these SNPs can cause resistance to some medicines. Read more…
Drug and substance abuse is one of the greatest challenges facing most teenagers and adults in the modern world. As the cases of drug abuse and addiction continue to rise every day, so many people are usually interested in finding the best recovery centers to help them or their loved ones refrain from this dangerous habit.
It is true that there are so many rehabilitation centers in various states in the U.S. but not all of them may offer the best services that suit the particular condition of your beloved one. For example, if you are looking for the best drug rehabilitation Michigan has to offer, you have to take your time to evaluate the personal condition of your beloved one and the overall qualities of that particular facility.
The treatment plan
Most patients normally struggle so hard with the withdrawal symptoms, especially when they are heavily addicted to a particular drug or alcoholic drink. It is therefore important to ensure that the selected facility provides the ultimate treatment plan that goes inline with the current condition of the patient. A good example is the administration of detoxification plans. This method helps in liberating the patient from drug addiction, thus making it easier to quit this habit at a faster rate. Read more…
Head injury is trauma/injury (blunt injury or non-blunt head injury) to head, which also may or may not include brain injury. There are various types of head injuries. A head injury may be open or close. In close head injury (mostly blunt injury), the dura mater remains intact. There may be fracture of skull.
How common is head injury?
The incidence of head injury as well as death due to head injury (and brain injury) varies in different countries. For example, the incidence of new cases of head injury is approximately 300 per 100,000 populations per year in most developed countries. The death rate varies e.g. in UK (United Kingdom) the death rate from head injury is nine per 100,000 populations per year, whereas in US and North America it is as high as 25, per 100,000 populations per year.
Head injury commonly leads to following problems:
- Laceration (cut injury) scalp and hemorrhage from scalp.
- Fracture of skull
- Edema of brain tissue, which result in rain in intracranial pressure which if left untreated may damage brain Read more…
Sudden cardiac arrest is literally the taking away of your breath in an instant. It can happen to anyone and is turning from mildly rare to increasingly common. The heart ceases to beat suddenly thus resulting in the stoppage of cardiac function. Stopping of the heart leads to losing of consciousness and breathing. There will also be an absence of blood pressure and pulse. The person can lose life within a space of minutes if resuscitation efforts aren’t carried out right away. The terms given for it by doctors are Sudden Cardiac Death and Sudden Death.
* Ventricular Fibrillation: Being the commonest of cardiac arrest causes, it happens when chaotic electrical activity replaces the heart muscle contraction – which includes electrical, normal and regular activation – causing the stoppage of heart beat. Hence, the heart doesn’t pump blood to the various organs as well as the utmost important organ: the brain. If the brain doesn’t receive blood flow less than five minutes of the arrest, the consequences could let to the damaging of the brain permanently and/or death.
* Respiratory Arrest: If the breathing function stops, oxygen doesn’t reach the heart leading to cardiac arrest.
* Other Causes: Drowning, electrocution, trauma and choking.
So What Leads to Cardiac Arrest? What Can You Do?
* Not eating healthy that is regularly consuming tropical oils and high saturated fats accelerates atherosclerosis, coronary heart disease, and obesity. A person’s cholesterol level must never be more than 200. Plus comparing to HDL, total cholesterol mustn’t exceed 5 times). Switching to heart healthy diet and a lot of exercise can help maintain the required level of cholesterol. Read more…
HIV has unique ability to evade the immune system of host. By evading the immune system the HIV gets the first foothold on a host (human) and evades the control and elimination of infection by the host. There are several mechanisms by which HIV evade the host immune system.
After getting the foothold in a human host, the HIV establishes a sustained level of replication of virus. The new generations of HIV also evade the host immune system by mutation and recombination and maintain viral diversity. Due to very high rate of virus replication as well as continuous mutation (responsible for vaccine ineffectiveness) the neutralizing antibodies that are formed by host defense can not neutralize the rapidly replicating and continuously mutating HIV.
The envelope proteins gp120 and gp41 are the main targets of neutralizing antibodies against HIV. But these neutralizing antibodies are evaded by HIV, by increased glycosylation of the envelope, by changing the primary sequence of the envelope, and masking of neutralizing epitopes. Read more…