Generally adverse reactions of blood transfusion are (1) non immune mediated and (2) immune mediated. Fortunately the common adverse reactions that occurs after blood transfusion are mild and serious adverse reactions occur only rarely, if ever.

The blood transfusion may also be complicated by transmission of infectious agents, such as virus, bacteria, and other infectious agents. Fortunately the transmission of infectious agents is also rare, especially viral transmissions are becoming rarer due to pretransfusion screening of donor’s blood.

What are the non immune mediated adverse reactions that can occur?

The non immune mediated adverse reactions that can occur after transfusion of blood and blood components are volume overload, hypothermia (subnormal body temperature), electrolyte imbalance (mainly toxicity), iron overload, hypotensive reactions and immunomodulation etc.

Generally adverse reactions of blood transfusion are (1) non immune mediated and (2) immune mediated. Fortunately the common adverse reactions that occurs after blood transfusion are mild and serious adverse reactions occur only rarely, if ever.

The blood transfusion may also be complicated by transmission of infectious agents, such as virus, bacteria, and other infectious agents. Fortunately the transmission of infectious agents is also rare, especially viral transmissions are becoming rarer due to pretransfusion screening of donor’s blood.

What are the non immune mediated adverse reactions that can occur?

The non immune mediated adverse reactions that can occur after transfusion of blood and blood components are volume overload, hypothermia (subnormal body temperature), electrolyte imbalance (mainly toxicity), iron overload, hypotensive reactions and immunomodulation etc.